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Updated: Aug 16, 2025

Corneal Donor Tissue Preparation for Endothelial Keratoplasty
Published on: June 12, 2012
Disparities in Access to Corneal Tissue in the Developing World
Catherine Liu1, Hajirah N Saeed1
1Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, United States.
Corneal disease blindness is a global issue. This review examines disparities in corneal donor tissue supply and demand, proposing solutions for equitable access to sight-restoring keratoplasty worldwide.
Area of Science:
- Ophthalmology
- Public Health
- Regenerative Medicine
Background:
- Corneal disease represents a significant global cause of blindness.
- Keratoplasty is the primary treatment for many blinding corneal conditions.
- Unequal access to corneal transplantation, particularly donor tissue, exacerbates disparities in sight restoration.
Approach:
- This review identifies current global disparities in corneal donor tissue supply and demand.
- It explores methods for accessing corneal tissue for transplantation.
- The review proposes strategies to promote equitable access to corneal tissue and treatment.
Key Points:
- A significant gap exists between the need for and availability of corneal donor tissue.
- Developing nations often face the greatest burden of corneal disease but have the least access to donor tissue.
- Addressing these disparities is crucial for global eye health equity.
Conclusions:
- Equitable access to corneal transplantation requires addressing the global shortage of donor tissue.
- Innovative solutions are needed to bridge the gap between developed and developing regions.
- Promoting fair distribution and availability of corneal tissue can restore sight to more patients globally.
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