Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

258
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
258
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

442
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
442
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

174
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
174
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy01:16

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

507
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
507
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors01:24

Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors

499
Peptic ulcer disease, commonly called PUD, represents a multifaceted condition characterized by disruptions in the lining of the gastrointestinal (GI)  tract. Central to the protection of the gastrointestinal lining is the mucosal-bicarbonate barrier. This physiological defense mechanism is a formidable shield against the corrosive effects of gastric acid and pepsin secretion in the stomach. Its role is pivotal in maintaining the structural integrity of the stomach's inner lining.
499
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

388
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
388

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Excitation Spectra of the ^{12}C(p,d) Reaction near the η^{'}-Meson Emission Threshold Measured in Coincidence with High-Momentum Protons.

Physical review letters·2026
Same author

<i>Glaphyrus festivus</i> Ménétriés, 1836 and related species in Turkey and Armenia (Coleoptera, Glaphyridae).

ZooKeys·2026
Same author

Author Correction: An asymmetric fission island driven by shell effects in light fragments.

Nature·2025
Same author

Impact of Cold Plasma Treatment on the Shelf Life and Metabolite Profiles of Strawberries during Storage.

ACS food science & technology·2025
Same author

An asymmetric fission island driven by shell effects in light fragments.

Nature·2025
Same author

Quasi-real-time range monitoring by in-beam PET: a case for <sup>15</sup>O.

Scientific reports·2023

Related Experiment Video

Updated: Aug 16, 2025

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

255

BLEPHARITIS AND HELICOBACTER-ASSOCIATED GASTRODUODENAL DISEASES (REVIEW).

E Kazantseva1, A Frolov1, M Frolov1

  • 1Peoples' Friendship University of Russia, Mosсow, Russia.

Georgian Medical News
|December 20, 2022
PubMed
Summary

Helicobacter pylori infection may play a role in eyelid inflammation (blepharitis). Evidence suggests links through harmful compounds, eye cytology changes, and bacteria in tear fluid, pointing to inflammation, endothelial dysfunction, and oxidative stress.

More Related Videos

Author Spotlight: Gastric Epithelial Cell Responses in Helicobacter pylori infection
08:24

Author Spotlight: Gastric Epithelial Cell Responses in Helicobacter pylori infection

Published on: July 5, 2024

738
Mouse Models Of Helicobacter Infection And Gastric Pathologies
07:43

Mouse Models Of Helicobacter Infection And Gastric Pathologies

Published on: October 18, 2018

20.4K

Related Experiment Videos

Last Updated: Aug 16, 2025

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

255
Author Spotlight: Gastric Epithelial Cell Responses in Helicobacter pylori infection
08:24

Author Spotlight: Gastric Epithelial Cell Responses in Helicobacter pylori infection

Published on: July 5, 2024

738
Mouse Models Of Helicobacter Infection And Gastric Pathologies
07:43

Mouse Models Of Helicobacter Infection And Gastric Pathologies

Published on: October 18, 2018

20.4K

Area of Science:

  • Ophthalmology
  • Gastroenterology
  • Microbiology

Background:

  • Blepharitis is a common inflammatory eyelid condition.
  • Helicobacter pylori (H. pylori) is a bacterium often associated with gastrointestinal issues.
  • Emerging evidence suggests a potential link between H. pylori infection and ocular surface diseases.

Purpose of the Study:

  • To investigate the relationship between H. pylori infection and blepharitis.
  • To analyze existing studies on the association between H. pylori and inflammatory eye diseases.
  • To explore potential pathogenetic mechanisms linking H. pylori to blepharitis.

Main Methods:

  • Systematic review and analysis of existing research data.
  • Examination of studies reporting H. pylori presence in ocular samples (e.g., lacrimal fluid).
  • Evaluation of studies assessing ocular changes post-H. pylori eradication.

Main Results:

  • Studies indicate the release of harmful volatile compounds (ammonia, hydrogen nitrate, hydrogen cyanide) in H. pylori-infected patients.
  • Restoration of ocular surface cytology following H. pylori eradication was observed.
  • Detection of H. pylori in the lacrimal fluid of affected individuals.

Conclusions:

  • H. pylori infection may have a pathogenetic or mediated role in blepharitis.
  • Three primary mechanisms are proposed: chronic inflammation, endothelial dysfunction, and oxidative stress.
  • Further research is warranted to elucidate the precise role of H. pylori in blepharitis.