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Updated: Aug 16, 2025

A Unified Methodological Framework for Vestibular Schwannoma Research
Published on: June 20, 2017
[Research progress on non-surgical treatment of vestibular schwannomas]
Maoxiang Xu1, Yumeng Jiang1, Qingxiu Yao1
1Department of Otorhinolaryngology Head and Neck Surgery,Shanghai Jiao Tong University Affiliated Sixth People's Hospital,Shanghai,200233,China.
Abstract:
At present, the main treatment for vestibular schwannomas is surgery. Considering the risk of multiple complications from surgery and the subjective and objective conditions of patients, a non-surgical treatment modality, namely stereotactic radiotherapy, has gradually been included in the treatment of vestibular schwannomas. Studies have shown that Gamma Knife therapy has a more prominent therapeutic effect on smaller tumors and can alleviate facial nerve disorders caused by space occupying of tumor mass. Cyberknife not only has a better effect on tumor control, but also has an ideal retention rate for patients' auditory function. Proton beam therapy has also been gradually applied to the treatment of vestibular schwannomas, but the effect of treatment remains to be further studied. Drug therapy includes a variety of target inhibitors and anti-angiogenic drugs. At present, drug treatment focuses more on preclinical research. This article reviews the clinical research of various radiotherapy and the progress of drug treatment.

