Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Surgical margins for soft-tissue sarcoma.

A Rydholm1, B Rööser

  • 1Department of Orthopedics, University Hospital, Lund, Sweden.

The Journal of Bone and Joint Surgery. American Volume
|September 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Simple guidelines for efficient referral of soft-tissue sarcomas: a population-based evaluation of adherence to guidelines and referral patterns.

The Journal of bone and joint surgery. American volume·2012
Same author

Nonrandom secondary chromosome-aberrations in liposarcomas with t(12, 16).

International journal of oncology·2011
Same author

Nonrandom secondary chromosome-aberrations in synovial sarcomas with t(x-18).

International journal of oncology·2011
Same author

Deep-seated ordinary and atypical lipomas: histopathology, cytogenetics, clinical features, and outcome in 215 tumours of the extremity and trunk wall.

The Journal of bone and joint surgery. British volume·2008
Same author

Chest wall sarcoma: outcome in 22 patients after resection requiring thoracic cage reconstruction.

Sarcoma·2008
Same author

Identification of low-risk tumours in histological high-grade soft tissue sarcomas.

European journal of cancer (Oxford, England : 1990)·2007

Wide surgical margins for soft-tissue sarcomas show varied local recurrence rates. Subclassifying margins improves risk assessment, with deep tumors having higher recurrence than subcutaneous or intramuscular ones.

Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Soft-tissue sarcomas require precise surgical management.
  • Understanding local recurrence rates is crucial for patient outcomes.

Purpose of the Study:

  • To analyze local recurrence rates in soft-tissue sarcomas treated with surgery alone.
  • To evaluate the impact of different wide surgical margin classifications.

Main Methods:

  • Retrospective analysis of 81 patients with soft-tissue sarcomas.
  • Surgical margins were classified into three types of wide margins.
  • Minimum follow-up of six years or until death.

Main Results:

  • Local recurrence rates differed significantly across the three wide margin subgroups.

Related Experiment Videos

  • No correlation found between recurrence and histological grade.
  • Low recurrence (<10%) for subcutaneous and intramuscular lesions treated with myectomy.
  • Higher recurrence (30%) for deep tumors not treated with myectomy.
  • Conclusions:

    • Subclassifying wide surgical margins is valuable for predicting soft-tissue sarcoma recurrence.
    • Specific margin types (subcutaneous, intramuscular with myectomy) yield favorable outcomes.
    • Deep tumors necessitate careful consideration due to higher recurrence risk.