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Nano-Engineered Surface Comprising Metallic Dendrites for Biomolecular Analysis in Clinical Perspective
Rohini Kumari1, Daphika S Dkhar1, Supratim Mahapatra1
1Laboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi 221005, India.
Biosensors
|December 23, 2022
Summary
Metallic nanodendrites, with their unique 3D structures and large surface areas, offer enhanced conductivity and catalytic activity. This review highlights their use in developing advanced biosensors for detecting various analytes.
Area of Science:
- Materials Science
- Nanotechnology
- Analytical Chemistry
Background:
- Metallic nanodendrites are 3D nanostructured materials with hierarchical self-assembled branches.
- Their unique morphology provides large active surface areas, enhancing catalytic activity and conductivity.
- These properties make them promising for fabricating advanced sensors.
Purpose of the Study:
- To review the properties and synthesis of metallic nanodendrites.
- To summarize the application of nanodendrite-engineered biosensors for detecting diverse analytes.
- To discuss the limitations and future potential of nanodendrite-based biosensors.
Main Methods:
- Review of existing literature on metallic nanodendrites.
- Analysis of synthesis methods for nanodendrite fabrication.
- Compilation of studies on nanodendrite-based biosensor applications.
Main Results:
- Nanodendrites exhibit superior catalytic activity and conductivity due to their high surface area.
- Nanodendrite-engineered biosensors demonstrate effective monitoring of small molecules, macromolecules, metal ions, and cells.
- Various real matrices have been utilized for biosensing applications.
Conclusions:
- Metallic nanodendrites are highly effective building blocks for advanced biosensor development.
- Further research into their limitations and potential can drive innovation in sensing technologies.
- Nanodendrite-based biosensors offer a promising platform for diverse analytical applications.

