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Identification of a novel allele with a frameshift mutation, HLA-DRB4*01:165N, using next-generation sequencing

Qian Hu^1,2, Caitlyn Burns¹, Connie McKinley¹

¹Histocompatibility and Immunogenetics Laboratory, Alberta Precision Laboratories, Calgary, Alberta, Canada.

|December 26, 2022

Abstract:

HLA-DRB4*01:165N exhibits deletion of a nucleotide in exon 3, producing a premature stop codon.

Keywords:

DRB4 next-generation sequencing null allele

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