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Risk Factors for Superficial Thrombophlebitis: A Retrospective Case Control Study
Miri Schamroth Pravda1, Daniel Yehuda2, Nili Schamroth Pravda3
1Department of Internal Medicine A, Meir Medical Center, Kfar Saba, Israel, Department of Intensive Care Unit, Wolfson Medical Center, Holon, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
The Israel Medical Association Journal : IMAJ
|December 27, 2022
Summary
Superficial thrombophlebitis (STP) risk factors include a history of venous thromboembolism (VTE) or STP, immobilization, varicose veins, inherited thrombophilia, and obesity. These clinical factors independently predict hospital presentation for STP.
Area of Science:
- Vascular Medicine
- Hematology
Background:
- Limited data exists on risk factors for superficial thrombophlebitis (STP) presenting to hospitals.
- Understanding these factors is crucial for patient risk stratification and management.
Purpose of the Study:
- To investigate and stratify clinical and laboratory risk factors for superficial thrombophlebitis (STP).
- Identify key predictors for STP in a hospital-presenting cohort.
Main Methods:
- Retrospective case-control study design.
- Comparison of 151 patients with STP against age- and gender-matched controls.
- Collection of data on clinical risk factors and five blood indices.
Main Results:
- Significant risk factors identified: varicose veins, recent immobilization, obesity, history of VTE or STP, and inherited thrombophilia.
- Multivariate analysis confirmed these as independent predictors.
- History of VTE/STP (OR 35.7) and immobilization (OR 22.3) showed the highest risk.
- Mean platelet volume was also higher in STP cases.
Conclusions:
- A history of VTE or STP, immobilization, varicose veins, inherited thrombophilia, and obesity are independent clinical risk factors for hospital-presenting STP.
- These findings aid in identifying high-risk individuals for targeted prevention and treatment strategies.
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