Prioritizing Pituitary Adenoma Care in Pakistan: Analysis from an Epidemiological Study

Area of Science:

• Neurosurgery
• Endocrinology
• Oncology

Background:

• Pituitary adenomas represent a significant health burden, particularly in Pakistan.
• Understanding demographic and clinical profiles is essential for effective management.
• Non-malignant brain tumors require focused attention within healthcare systems.

Purpose of the Study:

• To identify symptoms, risk factors, and optimize diagnosis, treatment, and management of pituitary adenomas.
• To reduce prolonged disability associated with pituitary adenomas.
• To inform healthcare strategies for pituitary adenoma care in Pakistan.

Main Methods:

• Retrospective analysis of 277 patients with histopathologically diagnosed pituitary adenomas.
• Data collected from 32 tertiary care neurosurgical centers in Pakistan.
• Information included demographics, tumor characteristics, treatment modalities, and follow-up outcomes.

Main Results:

• The mean age at diagnosis was 39.8 years; 63.5% of patients were male.
• Males in younger age groups and the working class were predominantly affected.
• Gross total resection was achieved in 56% of cases; pediatric cases were rare (4.7%).

Conclusions:

• Pituitary adenomas disproportionately affect younger males, imposing a substantial socio-economic burden.
• Effective management requires addressing gender and age disparities.
• Integrating digital health technologies for follow-up and adjuvant treatment is recommended.