Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anionic Chain-Growth Polymerization: Overview01:20

Anionic Chain-Growth Polymerization: Overview

2.1K
The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heterocoagulation of Inorganic Pigments for Solvent-Based Recycling of Polystyrene.

ChemSusChem·2026
Same author

Two-Photon Responsive Amphiphilic Photoswitches as Molecular Modulators of Lipid Order and Curvature.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Gradient Copolymers: A Complex Comonomer Incorporation Reality behind the Perfect Ideal.

ACS polymers Au·2026
Same author

Author Correction: Steric stabilization-independent stealth cloak enables nanoreactors-mediated starvation therapy against refractory cancer.

Nature biomedical engineering·2026
Same author

Author Correction: Steric stabilization-independent stealth cloak enables nanoreactors-mediated starvation therapy against refractory cancer.

Nature biomedical engineering·2025
Same author

Dimensionally Stable Nanofibrous Nonwoven as a Flexible Dynamic Emissivity Switching Temperature-Regulating Material.

Advanced materials (Deerfield Beach, Fla.)·2025

Related Experiment Video

Updated: Aug 15, 2025

Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
09:09

Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

Published on: February 27, 2016

10.1K

Poly(N-allyl acrylamide) as a Reactive Platform toward Functional Hydrogels.

Jente Verjans1, Tomáš Sedlačík1, Valentin Victor Jerca2

  • 1Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, B-9000 Ghent, Belgium.

ACS Macro Letters
|January 3, 2023
PubMed
Summary

This study introduces poly(N-allyl acrylamide) (PNAllAm) for creating functional hydrogels. This new polymer platform allows for tunable hydrogel properties, such as adjusting the transition temperature, via thiol-ene chemistry.

More Related Videos

Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues
11:31

Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues

Published on: August 28, 2014

13.5K
Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

29.1K

Related Experiment Videos

Last Updated: Aug 15, 2025

Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
09:09

Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

Published on: February 27, 2016

10.1K
Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues
11:31

Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues

Published on: August 28, 2014

13.5K
Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

29.1K

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Biomaterials Engineering

Background:

  • Developing novel polymer platforms is crucial for advanced functional materials.
  • Hydrogels with tunable properties are in demand for various applications.
  • Poly(N-allyl acrylamide) (PNAllAm) offers potential as a versatile polymer precursor.

Purpose of the Study:

  • To synthesize poly(N-allyl acrylamide) (PNAllAm) from poly(methyl acrylate) (PMA).
  • To characterize PNAllAm and determine its properties, including its lower critical solution temperature.
  • To utilize PNAllAm in the preparation of functional hydrogels via thiol-ene chemistry and investigate the impact of functional thiols on hydrogel properties.

Main Methods:

  • Organocatalyzed amidation of poly(methyl acrylate) with allylamine to synthesize PNAllAm.
  • Characterization using 1H NMR spectroscopy, size exclusion chromatography (SEC), and turbidimetry.
  • Hydrogel formation via photoinitiated thiol-ene click chemistry using dithiothreitol (DTT) and mercaptoethanol (ME).

Main Results:

  • Successful synthesis and characterization of PNAllAm, with an estimated lower critical solution temperature of ~26 °C in water.
  • Formation of functional hydrogels using PNAllAm as a reactive platform.
  • Demonstrated modulation of hydrogel properties, specifically a decrease in volume-phase transition temperature with increasing mercaptoethanol content.

Conclusions:

  • A straightforward method for preparing PNAllAm from PMA was established.
  • PNAllAm serves as a valuable reactive polymer platform for generating functional hydrogels.
  • The incorporation of functional thiols allows for tuning the thermoresponsive behavior of the resulting hydrogels.