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Sticking to your side: A niche for the development of ipsilateral retinal projections
Madison T Gray1, Julie L Lefebvre1
1Program for Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Canada.
Neuron
|January 5, 2023
Abstract:
Visual impairments in albinism result from decreased ipsilateral retinal projections. In this issue of Neuron, Slavi, Balasubramanian, and colleagues1 demonstrate how low CyclinD2 in the ciliary marginal zone perturbs generation of ipsilaterally projecting RGCs and that restoring CyclinD2 improves vision in albino mice.
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