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Exercise Mode in Heart Failure: A Systematic Review and Meta-Analysis
Jamie Edwards1, Nesan Shanmugam2, Robin Ray2
1School of Psychology and Life Sciences, Canterbury Christ Church University, North Holmes Road, Canterbury, Kent, CT1 1 QU, UK.
Sports Medicine - Open
|January 9, 2023
Summary
High-intensity interval training (HIIT) significantly improves peak oxygen uptake and left-ventricular ejection fraction in heart failure patients compared to moderate-intensity training. Combined training shows no difference from moderate-intensity training.
Area of Science:
- Cardiology and Exercise Physiology
- Heart Failure Management
- Rehabilitation and Sports Medicine
Background:
- Optimizing exercise prescription is crucial for heart failure (HF) patients with preserved (HFpEF) or reduced (HFrEF) ejection fraction.
- This meta-analysis compares moderate-intensity training (MIT), combined training (CT), and high-intensity interval training (HIIT) for improving cardiorespiratory fitness and clinical parameters in HF.
Approach:
- A systematic search identified randomized controlled trials published between 1990 and May 2021.
- Studies compared MIT against CT or HIIT, analyzing effects on peak oxygen consumption (VO2), left-ventricular ejection fraction (LVEF), and diastolic function markers.
Key Points:
- High-intensity interval training (HIIT) significantly improved peak VO2 and LVEF in HF patients compared to moderate-intensity training (MIT).
- No significant differences were observed between MIT and combined training (CT) for peak VO2 or LVEF.
- HIIT's superiority over MIT was consistent across HF phenotypes, except for peak VO2 in HFpEF.
Conclusions:
- High-intensity interval training (HIIT) is a more effective exercise strategy than moderate-intensity training (MIT) for enhancing cardiorespiratory fitness and cardiac function in heart failure.
- Combined training (CT) offers similar benefits to MIT, indicating that resistance exercise inclusion does not impede aerobic adaptations.
- These findings support the integration of HIIT into exercise protocols for heart failure management.
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