Related Experiment Video
Updated: Aug 14, 2025

Development of a Noninvasive, Laser-Assisted Experimental Model of Corneal Endothelial Cell Loss
Published on: April 24, 2020
Corneal Ectasia after Laser-Assisted Small-Incision Lenticule Extraction: The Case for an Enhanced Ectasia Risk
Siamak Zarei-Ghanavati1, Samira Hassanzadeh2, Renato Ambrósio3
1Eye Research Center, Department of Ophthalmology, Mashhad University of Medical Sciences, Mashhad, Iran.
Purpose:
To present a case of asymmetric progressive corneal ectasia following femtosecond laser-assisted small-incision lenticule extraction.
Methods:
After obtaining a patient's consent, preoperative and postoperative findings were represented in this case report.
Results:
A 29-year-old woman presented with normal preoperative Placido disk-based corneal topography and tomographic findings. The corrected refractive error was -4.00 and -4.50 -1.00 × 177 in the right and left eye, respectively, with a maximal lenticule thickness of 87 and 115 μm OD/OS. Twenty months postoperatively, the patient presented with decreased vision in the left eye and mild ectatic changes in corneal shape in both eyes. The retrospective evaluation of the integrated rotating Scheimpflug tomography (Pentacam; Oculus, Wetzlar, Germany) and corneal biomechanical (Corvis ST) assessment revealed moderate susceptibility for corneal ectasia in the right eye and a significant corneal ectasia in the left eye.
Conclusion:
This case corroborates the need for an enhanced multimodal approach to characterize the risk for postoperative corneal ectasia after laser vision correction.

