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A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
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Metastatic Jejunal Renal Cell Carcinoma Intussusception Presenting as Melena
Emad Elmusa1, Muhammad Waleed Raza1, Ameer Hamza1
1Internal Medicine, HCA Florida Orange Park Hospital, Orange Park, USA.
Cureus
|January 19, 2023
Summary
Metastatic renal cell carcinoma (RCC) rarely spreads to the small bowel, but can cause gastrointestinal bleeding. Push enteroscopy aided in diagnosing a rare case of jejunal metastasis causing intussusception.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Pathology
Background:
- Renal cell carcinoma (RCC) typically metastasizes to the lungs, with small bowel involvement being uncommon.
- Gastrointestinal (GI) bleeding is a frequent presentation of small bowel metastasis.
- Small bowel intussusception can rarely be caused by a metastatic mass acting as a lead point.
Observation:
- A male patient presented with melena as his primary symptom, denying abdominal pain or nausea.
- Push enteroscopy identified a jejunal mass.
- Computed tomography (CT) revealed small bowel intussusception.
Findings:
- Histopathology confirmed the jejunal mass to be metastatic renal cell carcinoma.
- The patient underwent surgical resection and anastomosis for the condition.
Implications:
- This case highlights the diagnostic utility of push enteroscopy for detecting small bowel metastasis from RCC.
- Early diagnosis and intervention are crucial for managing rare metastatic presentations of RCC.
- Understanding rare metastatic patterns aids in comprehensive patient care and treatment strategies.
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