Related Experiment Video
Updated: Aug 13, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Composition, Treatment, and Outcomes by Radiologically Defined Thrombus Characteristics in Acute Ischemic Stroke
Saurav Das1, Eric D Goldstein2, Adam de Havenon3
1Department of Neurology, University of Kentucky College of Medicine, Lexington (S.D.).
Cervicocephalic thrombi in acute ischemic stroke patients have distinct imaging features. Understanding clot characteristics is crucial for guiding stroke treatment and prevention strategies.
Area of Science:
- Neuroimaging
- Vascular Neurology
- Pathology
Background:
- Cervicocephalic thrombi are observed in acute ischemic stroke.
- Imaging characteristics can indicate the stroke's cause and inform treatment.
Purpose of the Study:
- To review the epidemiology, imaging features, and histology of cervicocephalic thrombi.
- To assess thrombi response to medical and endovascular therapies.
Main Methods:
- Literature review of neurovascular imaging studies.
- Analysis of radiographic and morphological thrombus characteristics.
- Evaluation of histologic clot composition.
Main Results:
- Occlusive and nonocclusive thrombi present differently on imaging.
- Clot characteristics influence treatment selection.
- Response to therapies varies based on thrombus properties.
Conclusions:
- Further research is needed for a classification system for partially occlusive thrombi.
- A validated classification could improve stroke treatment and prevention.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis I: Introduction
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Acute Coronary Syndrome III: Diagnostic Studies

