Progress of Molecular Display Technology Using Saccharomyces cerevisiae to Achieve Sustainable Development Goals

Area of Science:

• Biotechnology
• Synthetic Biology
• Microbial Engineering

Background:

• Yeasts have a long history of use in fermentation and as hosts for producing compounds.
• Genetic engineering allows for recombinant protein production in yeast and bacterial systems.
• Saccharomyces cerevisiae is a well-established model organism for genetic manipulation.

Purpose of the Study:

• To review molecular yeast display technologies, their principles, and applications.
• To describe Saccharomyces cerevisiae strains developed using molecular display for sustainable development.
• To link yeast display applications with United Nations Sustainable Development Goals.

Main Methods:

• Summarizing various molecular yeast display technologies.
• Explaining the principles behind yeast cell surface protein production.
• Detailing the generation of engineered Saccharomyces cerevisiae strains.

Main Results:

• Molecular display technology enables designed proteins to be presented on yeast cell surfaces.
• Engineered yeast strains exhibit novel functionalities.
• Applications of molecular displayed yeast cells are mapped to Sustainable Development Goals.

Conclusions:

• Molecular yeast display is a powerful tool for engineering yeast functionalities.
• This technology contributes to sustainable development through diverse applications.
• Saccharomyces cerevisiae serves as a versatile platform for molecular display innovations.