Related Experiment Video
Updated: Aug 13, 2025

07:34
Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
Published on: December 15, 2023
2.3K
[Role of Microbiota in Stroke Pathogenesis]
Shuichi Tonomura1, Masafumi Ihara
1Department of Vascular Physiology, National Cerebral and Cardiovascular Center Research Institute.
No Shinkei Geka. Neurological Surgery
|January 22, 2023
Summary
The gut microbiome influences stroke risk and progression by interacting with vascular factors. Ongoing research aims to uncover personalized microbiome-based therapies for stroke.
Area of Science:
- Microbiome research
- Neuroscience
- Vascular biology
Background:
- Stroke is a leading cause of death and disability in Japan.
- Host-microbial interactions are increasingly recognized in systemic diseases.
- The gut microbiome's role in health and disease is a rapidly evolving field.
Conclusions:
- The microbiome is a significant factor in stroke development and progression.
- Understanding host-microbial interactions offers potential for novel stroke prevention and treatment strategies.
- Personalized microbiome-based therapies hold promise for future stroke management.

