Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

2.0K
2.0K
Conserved Binding Sites01:49

Conserved Binding Sites

4.3K
Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...
4.3K
Assembly of Signaling Complexes01:30

Assembly of Signaling Complexes

5.8K
Multiprotein signaling complexes are formed in a dynamic process involving protein-protein interactions at the cytoplasmic domain of transmembrane receptors or enzymatic and non-enzymatic proteins associated with the receptor. These complexes ensure the activation and propagation of intracellular signals that regulate cell functions.
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...
5.8K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

4.8K
Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
4.8K
Targets for Drug Action: Overview01:26

Targets for Drug Action: Overview

6.9K
Drugs target macromolecules to modify ongoing cellular processes. Primary drug targets include receptors, ion channels, transporters, and enzymes.
Receptors are either membrane-spanning or intracellular proteins, which upon binding a ligand, get activated and transmit the signal downstream to elicit a response. Drugs bind receptors, either mimicking the action of endogenous ligands or blocking the receptor activity to bring about a modified response. Nearly 35% of approved drugs target the G...
6.9K
Internal Receptors01:31

Internal Receptors

70.5K
Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.
70.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perception and action as one: Re-integrating research on human action through event files.

Psychological review·2026
Same author

Functional reserve mitigates cognitive-motor dual-task costs in older adults: insights from age, cohort, and behavioural strategies.

European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity·2026
Same author

Binding and retrieval of omitted responses in complex response sequences.

Attention, perception & psychophysics·2026
Same author

From prediction to control: Age-related dissociations between implicit regularity encoding and attentional modulation during perception-action integration.

Developmental cognitive neuroscience·2026
Same author

A Multiplexed Neural Code Governs Dynamic Perception-Action Reconfiguration during Response Inhibition.

Journal of cognitive neuroscience·2026
Same author

The sound of silence: Binding and retrieval of silence in distractor-response binding.

Attention, perception & psychophysics·2026
Same journal

Orthographic Neighbourhood Size Effects in Chinese Character Recognition: Small, Inconsistent, and Theoretically Ambiguous.

Journal of cognition·2026
Same journal

The Role of Different Thoughts in Tacit Coordination and Its Malleability by Interventions.

Journal of cognition·2026
Same journal

The Impact of Prior Beliefs about Volatility on Adaptive Behavior.

Journal of cognition·2026
Same journal

Proactive Control of Emotional Information in Adult ADHD.

Journal of cognition·2026
Same journal

Knowledge Gap Illustrations Spark Curiosity.

Journal of cognition·2026
Same journal

Centre-of-Mass Confounds Contribute to Familiar Size Stroop Effects with Boger and Firestone's 'Visual Anagrams'.

Journal of cognition·2026
See all related articles

Related Experiment Video

Updated: Aug 12, 2025

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm
12:12

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm

Published on: May 14, 2014

10.6K

Core Mechanisms in Action Control: Binding and Retrieval.

Andrea Kiesel1, Lisa R Fournier2, Carina G Giesen3

  • 1University of Freiburg, DE.

Journal of Cognition
|January 26, 2023
PubMed
Summary
This summary is machine-generated.

This collection explores action control, focusing on feature binding and retrieval. The Binding and Retrieval in Action Control (BRAC) framework integrates diverse findings, explaining how cognition serves goal-directed behavior.

Keywords:
ActionAction and perceptionCognitive ControlEvent cognition

More Related Videos

Measuring Nucleotide Binding to Intact, Functional Membrane Proteins in Real Time
08:33

Measuring Nucleotide Binding to Intact, Functional Membrane Proteins in Real Time

Published on: March 11, 2021

2.0K
Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

6.7K

Related Experiment Videos

Last Updated: Aug 12, 2025

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm
12:12

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm

Published on: May 14, 2014

10.6K
Measuring Nucleotide Binding to Intact, Functional Membrane Proteins in Real Time
08:33

Measuring Nucleotide Binding to Intact, Functional Membrane Proteins in Real Time

Published on: March 11, 2021

2.0K
Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

6.7K

Area of Science:

  • Cognitive Psychology
  • Neuroscience

Background:

  • Action control is crucial for goal-directed behavior and environmental interaction.
  • Cognitive processes are understood to support action preparation, execution, and regulation.
  • Existing research on action control is fragmented across various paradigms and models.

Purpose of the Study:

  • To introduce and explain the Binding and Retrieval in Action Control (BRAC) framework.
  • To provide an integrative account of action control research.
  • To overview 20 articles discussing sequential paradigms within the BRAC framework.

Main Methods:

  • The BRAC framework proposes feature binding and retrieval as core processes in action control.
  • The special collection analyzes various sequential paradigms through the lens of the BRAC framework.
  • This editorial synthesizes the framework's assumptions and the collection's findings.

Main Results:

  • The BRAC framework offers a unified explanation for a broad range of findings in action control research.
  • Feature binding and retrieval are identified as key functions underlying cognitive support for action.
  • The collection demonstrates the applicability of the BRAC framework across diverse experimental paradigms.

Conclusions:

  • The BRAC framework provides a cohesive model for understanding action control.
  • Integrating research through the BRAC framework enhances our comprehension of cognition's role in action.
  • Future research can leverage the BRAC framework for a more unified approach to action control studies.