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Online Circular Contrast Perimetry: A Comparison to Standard Automated Perimetry
Joshua Meyerov1, Yuanchen Deng1, Lazar Busija2,3
1St Vincent's Hospital Clinical School, University of Melbourne, Melbourne, Vic., Australia.
Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
|January 27, 2023
Summary
A new online circular contrast perimetry (OCCP) tool shows diagnostic accuracy comparable to standard automated perimetry (SAP) for glaucoma detection. This application holds promise for glaucoma screening and surveillance, including at-home use.
Area of Science:
- Ophthalmology
- Medical Technology
- Diagnostic Imaging
Background:
- Glaucoma diagnosis relies heavily on visual field testing.
- Standard automated perimetry (SAP) is a common but resource-intensive method.
- Novel, accessible perimetry tools are needed for widespread glaucoma screening.
Purpose of the Study:
- To validate and compare the diagnostic accuracy of a novel online circular contrast perimetry (OCCP) application.
- To assess OCCP's performance against standard automated perimetry (SAP) and optical coherence tomography (OCT).
Main Methods:
- Prospective cohort study involving 220 participants (125 controls, 95 glaucoma patients).
- Comparison of agreement, correlation, sensitivity, specificity, and AUC for OCCP, SAP, and OCT parameters.
- Evaluation of retinal nerve fiber layer and macular ganglion cell complex inner plexiform layer using OCT.
Main Results:
- OCCP demonstrated higher pointwise sensitivity than SAP.
- Strong correlation and agreement were observed between OCCP and SAP for global and regional indices.
- OCCP's mean deviation (MD) AUC (0.885±0.08) was comparable to SAP MD (0.851±0.08) and OCT parameters.
Conclusions:
- OCCP exhibits perimetric sensitivities and diagnostic accuracy similar to SAP and OCT for distinguishing glaucoma patients.
- OCCP shows potential as an effective tool for glaucoma surveillance and screening.
- The application may facilitate both in-clinic and at-home perimetry, expanding community testing accessibility.
