Related Experiment Video
Updated: Aug 12, 2025
07:57
An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
225
Association Between Antibiotic Prophylaxis Before Cystectomy or Stent Removal and Infection Complications: A
Luca Antonelli1, Kirby Sebro2, Abdelilah Lahmar3
1Department of Urology, Luzerner Kantonsspital, University of Lucerne, Lucerne, Switzerland; Department of Urology, Policlinico Umberto I, Sapienza University, Rome, Italy.
European Urology Focus
|January 29, 2023
Summary
Infectious complications are common after radical cystectomy, with high rates of urinary tract infections and surgical site infections. Antibiotic use and stent removal protocols vary widely, necessitating further research.
Area of Science:
- Urology
- Infectious Diseases
- Surgical Oncology
Background:
- Radical cystectomy patients frequently experience infectious complications like UTIs and SSIs.
- These complications lead to increased healthcare utilization, including emergency visits and readmissions, and elevated costs.
Conclusions:
- A high incidence of infectious complications following radical cystectomy is confirmed.
- There is substantial variability in antibiotic strategies and stent management, indicating a need for standardized protocols.
- Further prospective trials are warranted to optimize perioperative care and reduce infectious complications.
Related Concept Videos
01:26Urine Studies II: Urine Culture and Sensitivity Test
77
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
77
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
22
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
22
01:22Healthcare Associated Infections II: Preventive Measures
2.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
01:26Factors Affecting the Risk of Infection
12.1K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.1K
01:25Urinary Tract Infection II: Pathophysiology
26
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
26
01:27Combined Effects of Drugs: Synergism
4.4K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
4.4K