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Adrenal Lymphoma: Case Reports and Mini-review.
Emad Mofid Nassif Rezkallah1, Ragai Sobhi Hanna2, Wael Magdy Elsaify1
1General Surgery Department, James Cook University Hospital, Middlesbrough, England.
International Journal of Endocrinology and Metabolism
|January 30, 2023
Summary
Adrenal lymphoma is rare, with most cases secondary to systemic lymphoma. Diagnosis requires tissue biopsy, and while chemotherapy is standard, prognosis remains poor for these challenging adrenal tumors.
Area of Science:
- Oncology
- Endocrinology
- Pathology
Background:
- Adrenal lymphoma is a rare condition, presenting as primary adrenal lymphoma (PAL) or secondary to systemic lymphoma.
- Diffuse large B-cell non-Hodgkin lymphoma is the most common histological type of PAL.
Observation:
- This study reviewed 17 adrenal lymphoma cases, with 16 being secondary and 1 primary.
- Patients commonly present with fever, lumbar pain, and adrenal insufficiency symptoms.
- Primary adrenal lymphoma often appears as large, heterogeneous masses on imaging, but diagnosis requires biopsy.
Findings:
- Chemotherapy is the primary treatment for adrenal lymphoma, with surgery having a limited role.
- The overall prognosis for adrenal lymphoma is poor, with approximately one-third of patients achieving remission.
Implications:
- Accurate diagnosis of adrenal lymphoma relies on histopathological confirmation.
- Further research is needed to improve treatment strategies and patient outcomes for adrenal lymphoma.
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