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Colorectal Cancer Survival: A single-Centre Experience.

Emad M N Rezkallah1, Benjamin Perakath2

  • 1Emad Mofid Nassif Rezkallah, MBBCH, MSc, MRCS, Hereford County Hospital, Wye Valley NHS Trust, Hereford, UK.

Indian Journal of Surgical Oncology
|July 1, 2026
PubMed
Summary

Colorectal cancer (CRC) survival rates at a district hospital were evaluated. Factors like age, gender, and treatment influenced patient outcomes, with overall 5-year survival at 59.3%.

Keywords:
5-yearAgeColorectal cancerStageSurvival

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Area of Science:

  • Oncology
  • Public Health

Background:

  • Colorectal cancer (CRC) is a prevalent malignancy in the UK.
  • Survival rates for CRC patients can differ significantly across healthcare centers.
  • District hospitals play a crucial role in managing CRC patient outcomes.

Purpose of the Study:

  • To report 5-year survival rates for colorectal cancer patients treated at a district hospital.
  • To investigate the impact of various patient and treatment-related factors on CRC survival.
  • To compare local CRC survival data with national benchmarks.

Main Methods:

  • Retrospective review of 405 colorectal cancer patients who received curative treatment between 2017-2019.
  • Kaplan-Meier method used to analyze survival rates.
  • Cox regression models employed to assess the relationship between survival time and influencing variables.

Main Results:

  • Overall 5-year survival rate was 59.3% (2-year survival: 78.5%).
  • Five-year survival rates by stage: Stage I (80.9%), Stage II (67.3%), Stage III (55%), Stage IV (10.9%).
  • Lower survival rates were observed in male patients, those with colon cancer, patients over 50, those without curative resection, and those receiving adjuvant therapy.

Conclusions:

  • The district hospital's CRC survival rates are comparable to other centers, considering local population demographics.
  • Patient age, tumor location, gender, curative resection status, and adjuvant therapy significantly affect colorectal cancer survival.
  • These findings highlight the importance of personalized treatment strategies and further research into disparities in CRC outcomes.