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[Preparations of acetylsalicylic acid sustained-release tablets on hydrophilic matrix forms]
Die Pharmazie
|July 1, 1987
Abstract:
The aim of this study was to prepare a tablet with acetylsalicylic acid based on hydrophilic matrix form by means of polyvinyl alcohol. The liberation was carried out with the column dissolution-rate method. In contrast to other studies, the percentage of the cumulative liberation is decreased by increasing the drug concentration. Acetylsalicylic acid caused a decrease of the wetting and the rate of swelling.