Related Experiment Video

Updated: Aug 12, 2025

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells
12:04

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells

Published on: March 10, 2023

3.7K

Next generation sequencing reveals a novel HLA-C allele, HLA-C*16:201

Mirzokhid Rakhmanov1, Murielle Verboom2, Martin Bernheiden1

  • 1Freiburg University Medical Center, Faculty of Medicine, Institute for Transfusion Medicine and Gene Therapy, University of Freiburg, Freiburg, Germany.

HLA
|January 31, 2023
PubMed

Abstract:

HLA-C*16:201 differs from HLA-HLA-C*16:01:01 by one nucleotide substitution in codon 73 (ACT ->GCT).

Keywords:
HLA-C*next generation sequencing (NGS)novel HLA-allele

More Related Videos

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
08:07

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

10.2K
Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
08:48

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

Published on: October 25, 2016

8.6K

Related Experiment Videos

Last Updated: Aug 12, 2025

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells
12:04

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells

Published on: March 10, 2023

3.7K
Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
08:07

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

10.2K
Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
08:48

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

Published on: October 25, 2016

8.6K

Related Concept Videos

Next-generation Sequencing03:00

Next-generation Sequencing

92.0K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
92.0K

Articles linked to this work by shared authors, journal, and citation graph.

Treatment response to daratumumab in antibody-mediated kidney allograft rejection: evidence from serial protocol biopsies.

Clinical kidney journal·2026

Outcomes and treatment of early detectable donor-specific antihuman leukocyte antigen antibodies after lung transplantation: Insights from a 12-year experience.

The Journal of thoracic and cardiovascular surgery·2026

Comparison of the Prognostic Value of Three Different Single HLA Based Antibody Detection Assays.

HLA·2026

Neoantigenic properties of TP53 variants influence cancer risk in individuals with Li-Fraumeni syndrome.

EBioMedicine·2025

HLA-C*14:171, a New Allele With a Rare Extracellular α3 Domain.

HLA·2025

Development of Non-HLA Antibodies and Their Association With Antibody-Mediated Rejection in Pediatric Kidney Transplant Recipients.

Transplant international : official journal of the European Society for Organ Transplantation·2025

Identification of the Novel HLA-B*57:212 Allele by Next-Generation Sequencing.

HLA·2026

Identification of Two Novel HLA-DQB1 Alleles, HLA-DQB1*02:239 and HLA-DQB1*02:271.

HLA·2026

Characterisation of the Novel HLA-DRB3*01:127 Allele by Next-Generation Sequencing.

HLA·2026

The Novel HLA-DQB1*06:03:60 Allele Identified by Next-Generation Sequencing and Confirmed by Nanopore Sequencing.

HLA·2026

Characterisation of the Novel HLA-A*23:163 Allele by Next-Generation Sequencing.

HLA·2026

Discovery of the Novel HLA-B*52:139 Allele in a Taiwanese Individual.

HLA·2026

Using human proteomic and lipidomic to exploration drug target of bladder cancer.

World journal of urology·2026

Genomic characteristics of performance traits and adaptation to heat stress in desert Barki sheep.

Archives animal breeding·2026

Bridging precision agriculture and human medicine through comparative genetics.

Nature reviews. Genetics·2026

Voxel-based analysis of glioblastoma topography and invasiveness using the Brain-Grid system: a multicenter retrospective study.

Journal of neurosurgery·2026

Association of Single-Nucleotide Polymorphisms, rs693 and rs1042031, in the APOB Gene with the Risk of Prostatic Diseases among Lebanese Males.

Asian Pacific journal of cancer prevention : APJCP·2026

Genomic characterization and biological activities of cell-free supernatant from Lactiplantibacillus pentosus CROT01 against clarithromycin-resistant Helicobacter pylori.

Frontiers in cellular and infection microbiology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us