Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

391
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
391
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

534
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
534
Allergic Reactions02:06

Allergic Reactions

28.1K
Overview
28.1K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

502
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
502
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

341
Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
341
Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

401
Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
401

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional and Structural Analysis of Auxetic Metamaterial Stent Designs for Thoracic Aortic Aneurysms Using Finite Element Simulation.

International journal for numerical methods in biomedical engineering·2026
Same author

The risk of glaucoma in chronic rhinosinusitis and allergic rhinitis: A systematic review and meta-analysis.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Fibrocytes as Key Mediators of Type 2 Inflammation in Asian Chronic Rhinosinusitis With Nasal Polyps.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same author

Retrieval-augmented generative AI enhances clinical reasoning in odontogenic sinusitis versus maxillary sinus mucositis.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2026
Same author

Clinical Features and Dental Pathologies in Maxillary Sinus Fungal Balls and Odontogenic Sinusitis.

The Laryngoscope·2026
Same author

Response to comment on Classification of chronic rhinosinusitis in Taiwan: A comprehensive analysis based on European position paper on rhinosinusitis and nasal polyps (EPOS) 2020.

Journal of the Formosan Medical Association = Taiwan yi zhi·2025

Related Experiment Video

Updated: Aug 12, 2025

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

1.9K

Recent Updates of Immunotherapy for Allergic Rhinitis in Children.

Chih-Feng Lin1, Yi-Tsen Lin1,2, Chun-Kang Liao1

  • 1Department of Otolaryngology, National Taiwan University Hospital, No. 7, ChungShan S. Rd., Zhongzheng Dist., Taipei City, 100225 Taiwan.

Current Otorhinolaryngology Reports
|February 1, 2023
PubMed
Summary

Allergen immunotherapy (AIT) offers disease-modifying benefits for children with allergies. This review summarizes recent advancements and updates on AIT safety and effectiveness in pediatric populations.

Keywords:
Allergen immunotherapyAllergic rhinitisAtopyChildrenTreatment

More Related Videos

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

586
Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

10.4K

Related Experiment Videos

Last Updated: Aug 12, 2025

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

1.9K
Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

586
Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

10.4K

Area of Science:

  • Pediatric Allergy and Immunology
  • Immunotherapy Research

Background:

  • Allergen immunotherapy (AIT) is a unique treatment for allergic diseases.
  • It demonstrates disease-modifying and preventative effects.
  • AIT is recognized as safe and effective in children.

Purpose of the Study:

  • To provide the most current information on AIT in children.
  • To highlight recent updates and research findings.
  • To discuss indications and benefits of AIT for pediatric allergic conditions.

Main Methods:

  • Review of recent scientific literature on pediatric AIT.
  • Synthesis of current research on AIT efficacy and safety.
  • Analysis of updates regarding AIT approaches in children.

Main Results:

  • AIT significantly improves symptoms and quality of life in children.
  • It reduces medication requirements and prevents new allergen sensitizations.
  • AIT can halt the progression of allergic rhinitis to asthma.
  • Ongoing research aims to address AIT disadvantages.

Conclusions:

  • AIT is a valuable treatment for pediatric allergic illnesses.
  • Individualized assessment is crucial for initiating AIT.
  • Recent advancements continue to refine AIT protocols for children.