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Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Published on: March 1, 2015

Dysphagia Advances in Head and Neck Cancer

J M Patterson¹, M Lawton¹

¹School of Health Sciences, Institute of Population Health/Liverpool Head and Neck Centre, University of Liverpool, 1.17 Thompson Yates Building, The Quadrangle, Brownlow Hill, Liverpool, L69 3GB USA.

Current Otorhinolaryngology Reports

|February 23, 2023

Summary

This review covers head and neck cancer-associated dysphagia, highlighting outcome measures and new treatments. Research is advancing, with ongoing trials focusing on speech and language pathology interventions for swallowing difficulties.

Area of Science:

Oncology
Otolaryngology
Speech and Language Pathology

Background:

Dysphagia is a common and debilitating side effect of head and neck cancer treatment.
Accurate measurement of dysphagia is crucial for evaluating treatment efficacy and guiding clinical decisions.

Purpose of the Study:

To summarize current literature on head and neck cancer-associated dysphagia.
To provide up-to-date evidence on dysphagia outcome measurement.
To review recent innovations in preventing, reducing, or remediating treatment-related dysphagia.

Main Methods:

Literature review of current evidence and ongoing clinical trials.
Analysis of patient-reported outcomes and clinical swallowing measures.
Examination of innovations in dysphagia management.

Main Results:

Both patient-reported and clinical measures are essential for assessing dysphagia.
Minimum important differences for some outcome measures have been established.
There is an increase in dysphagia-related trials, particularly for HPV-positive oropharyngeal cancer and speech-language pathology interventions.

Conclusions:

Further research is needed to establish a consensus on outcome measures for head and neck cancer dysphagia.
Treatment modifications hold potential for improving patient outcomes.
Several clinical trials are investigating the effectiveness of speech and language pathology interventions for dysphagia.

Keywords:

Deglutition disorders, Head and neck neoplasm Outcome measures Prehabilitation Speech-language pathology Treatment

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