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Updated: Aug 12, 2025

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
[Hypertension: what's new in 2022].
Grégoire Wuerzner1, Belén Ponte2, Antoinette Pechère-Bertschi2
1Service de néphrologie et hypertension, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Controlling high blood pressure remains challenging for many patients. Recent research highlights environmental factors, new therapeutic targets for pregnant individuals, and innovative strategies for resistant hypertension.
Area of Science:
- Cardiology
- Nephrology
- Obstetrics
Context:
- Hypertension management presents ongoing clinical challenges.
- Recent research highlights environmental and therapeutic factors influencing blood pressure control.
- Specific considerations are needed for hypertensive pregnant patients.
Purpose:
- To summarize key advancements in hypertension research from the past year.
- To discuss factors affecting blood pressure (BP) control.
- To propose novel therapeutic strategies for resistant hypertension.
Summary:
- Blood pressure (BP) control in hypertensive patients is difficult.
- Factors like temperature and sodium intake impact BP.
- New targets for pregnant hypertensive patients are proposed.
- The efficacy of nightly antihypertensive dosing is questioned.
- Endothelin blockade is presented as a strategy for resistant hypertension.
Impact:
- Provides clinicians with a concise overview of recent hypertension research.
- Informs clinical practice regarding BP management strategies.
- Highlights emerging therapeutic targets and challenges in hypertension treatment.
Related Concept Videos
Hypertension I: Introduction
Hypertension II: Pathophysiology
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension and Regulation of Blood Pressure
Hypertension IV: Drug Therapy and Lifestyle Modifications
Hypertension V: Nursing Management

