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Updated: Aug 12, 2025

Thermal Ablation for the Treatment of Abdominal Tumors

Thermal Ablation for the Treatment of Abdominal Tumors

Published on: March 7, 2011

Low temperature plasma ablation device for minimally invasive surgery.

Mingyang Sun¹, Guimin Xu¹, Guanjun Zhang¹

¹School of Electrical Engineering, State Key Laboratory of Electrical Insulation and Power Equipment, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, China.

The Review of Scientific Instruments

|February 1, 2023

Summary

This study presents a novel electrosurgical scalpel design using high-frequency square wave power to create low-temperature plasma for tissue ablation. The device successfully ablated pork, demonstrating potential for minimally invasive surgery.

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Area of Science:

Biomedical Engineering
Plasma Physics
Surgical Technology

Background:

Minimally invasive surgery requires precise tissue ablation tools.
Low-temperature plasma offers a non-thermal ablation mechanism.
Developing efficient power sources for plasma generation is crucial.

Purpose of the Study:

To design and simulate a high-frequency square wave power supply for an electrosurgical scalpel.
To investigate the generation of low-temperature plasma in saline solution for ablation.
To evaluate the performance of the device in tissue ablation.

Main Methods:

Design of a high-frequency square wave power supply.
Simulation and design of a minimally invasive electrosurgical scalpel.

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Saline discharge experiments to characterize plasma generation.

Pork ablation experiments to assess efficacy.

Main Results:

The electrosurgical scalpel successfully generated low-temperature plasma in saline.
Pork ablation was achieved using a 10 V, 100 kHz square wave voltage.
Ablation speed and area increased with higher voltage and frequency.
The device ablated tissue via plasma rather than thermal effects.

Conclusions:

The developed high-frequency square wave power supply effectively drives an electrosurgical scalpel for low-temperature plasma generation.
The device shows promise for minimally invasive surgical ablation with enhanced control.
Further optimization of voltage and frequency can improve ablation efficiency.