Related Experiment Video
Updated: Aug 12, 2025

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Revisiting Paraphrenia: A Case Report
Filipa Andrade1, Cláudia Reis1, Márcia Mota1
1Psychiatry, Centro Hospitalar Universitário de São João, Porto, PRT.
Paraphrenia, a psychotic disorder with delusions but preserved personality, is not in current diagnostic systems. This review examines its clinical relevance and classification challenges in psychiatry.
Area of Science:
- Psychiatry
- Psychopathology
- Clinical Psychology
Background:
- Paraphrenia is a chronic psychotic disorder characterized by delusions with preserved thought and personality.
- Historically, it was differentiated from schizophrenia and delusional disorder due to less personality deterioration.
- This diagnostic entity is not currently recognized in major classification systems.
Observation:
- A clinical vignette of a patient with paraphrenia-like symptoms was presented.
- The patient exhibited a strong delusional component with preserved personality and thought processes.
- The case highlights diagnostic challenges in current psychiatric practice.
Findings:
- The concept of paraphrenia presents classification difficulties within existing diagnostic frameworks.
- Cases resembling paraphrenia highlight limitations in current diagnostic systems for psychotic disorders.
- Revisiting paraphrenia is crucial for accurate diagnosis and understanding of complex psychotic presentations.
Implications:
- Accurate classification of paraphrenia is essential for appropriate patient management and treatment.
- Further research is needed to clarify the diagnostic boundaries of paraphrenia.
- Reintegrating or refining the concept of paraphrenia may improve diagnostic precision in psychiatry.
More Related Videos
05:52Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
09:55Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
Published on: March 8, 2018
Related Concept Videos
Personality Disorders: Paranoid and Schizoid
Paranoid Personality Disorder
Paranoid personality disorder is...
Psychosis: Goals of Pharmacotherapy
Psychosis and Antipsychotic Drugs: Overview
Drug Therapy
Antianxiety Medications
Personality Disorders: Schizotypal and Histrionic
Schizotypal Personality Disorder: Eccentric Behavior and Social Withdrawal
Schizotypal personality disorder is marked by odd or eccentric...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...