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Fluoroscopic Intraoperative Breast Neoplasm and Node Detection.

Roi Weiser1, Gabrielle C Manno1, Samuel H Cass1

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Summary
This summary is machine-generated.

Fluoroscopic Intraoperative Neoplasm and Node Detection (FIND) offers a less painful, more effective way to locate nonpalpable breast lesions compared to traditional wire localization. This technique also improves axillary node identification, aiding in targeted treatments.

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Area of Science:

  • Oncology
  • Radiology
  • Surgical Oncology

Background:

  • Preoperative localization is essential for nonpalpable breast lesions.
  • Traditional wire localization (WL) can be painful and costly.
  • Fluoroscopic Intraoperative Neoplasm and Node Detection (FIND) is a novel technique using intraoperative visualization of biopsy clips.

Purpose of the Study:

  • To evaluate the effectiveness of FIND compared to WL in improving negative margin rates for nonpalpable breast lesions.
  • To assess secondary outcomes including re-excision rates, specimen weight, and surgery time.
  • To determine the accuracy of FIND in localizing axillary nodes.

Main Methods:

  • Retrospective study of 459 patients (September 2016 - March 2021).
  • Comparison of breast and axillary node procedures using FIND versus wire localization (WL).
  • Analysis of margin status, re-excision rates, specimen weight, surgery time, and axillary node localization accuracy.

Main Results:

  • FIND procedures had a lower positive margin rate (5.1%) compared to WL (16.6%) (p=0.008).
  • Re-excision rates showed a trend towards being lower with FIND (7.6%) versus WL (14.6%) (p=0.125).
  • FIND achieved 100% axillary node localization, significantly higher than WL (80.1%) (p=0.019).

Conclusions:

  • FIND demonstrates value in localizing nonpalpable breast lesions with lower positive margins and a trend towards fewer re-excisions.
  • FIND provides accurate axillary node localization, crucial for targeted axillary dissection.
  • This visual localization method utilizes existing surgeon skills and equipment, potentially reducing patient discomfort and healthcare costs.