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Updated: Aug 12, 2025

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
Published on: September 20, 2024
Wavefront-guided PRK treatment of myopia using a refractive aberrometer
Elizabeth M Hofmeister1, John B Cason, Donna M Murdoch
1From the Ophthalmology Department, Naval Medical Center San Diego, San Diego, California; (Hofmeister, Cason, Murdoch); Johnson & Johnson Vision, Irvine, California (Yau, Wang, Parizadeh, Janakiraman, Kasthurirangan).
Wavefront-guided photorefractive keratectomy (PRK) is a safe and effective procedure for correcting myopia and astigmatism. This vision correction method significantly improves visual acuity and patient satisfaction.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Vision Science
Background:
- Myopic refractive errors, with or without astigmatism, affect a significant portion of the population.
- Photorefractive keratectomy (PRK) is a common surgical option for vision correction.
- Advancements in aberrometry and laser technology aim to improve PRK outcomes.
Purpose of the Study:
- To evaluate the safety, effectiveness, and patient-reported outcomes of wavefront-guided PRK.
- To assess the correction of myopic refractive errors with and without astigmatism using this technique.
Main Methods:
- A prospective, nonrandomized clinical investigation involving 334 eyes (167 patients).
- Wavefront-guided PRK was performed using the STAR S4 IR Excimer Laser System and iDESIGN wavefront measurements.
- Patients had myopia up to -8.00 D sphere and -4.00 D cylinder, with a maximum spherical equivalent (SE) of -10.00 D.
Main Results:
- At 6 months, 99.4% of eyes achieved 20/20 or better uncorrected distance visual acuity (UDVA).
- 85.5% of eyes had manifest refraction SE within 0.50 D of target, with a mean SE of -0.06.
- Patient-reported outcomes showed significant improvements in vision-related functioning and high satisfaction (98%).
Conclusions:
- Wavefront-guided PRK using the iDESIGN aberrometer is a safe and effective treatment for low to moderate myopia with or without astigmatism.
- The procedure is predictable and leads to high levels of patient satisfaction.
- This technology offers a reliable option for refractive error correction.
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