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Updated: Aug 11, 2025

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers
Published on: June 20, 2019
Crystallization behaviors regulations and mechanical performances enhancement approaches of polylactic acid (PLA)
Xipo Zhao1, Jiajie Yu2, Xinyu Liang2
1Hubei Provincial Key Laboratory of Green Materials for Light Industry, New Materials and Green Manufacturing Talent Introduction and Innovation Demonstration Base, Hubei University of Technology, Wuhan 430068, China; Hubei Longzhong Laboratory, Xiangyang 441000, China.
Abstract:
Polylactic acid (PLA) has attracted much attention because of its good biocompatibility, biodegradability, and mechanical properties. However, the slow crystallization rate of PLA during molding leads to its poor heat resistance, which limit its diffusion for many industrial applications. In this review, the relationship between PLA crystallization and its molecular structure and processing conditions is summarized. From the perspective of the regulation of PLA crystallization by organic nucleating agents, the research progress of organic micromolecule (e.g., esters, amides, and hydrazides), organic salt, supramolecular, and macromolecule nucleating agents on the crystallization behavior of PLA is mainly introduced. The nucleation mechanism of PLA is expounded by organic nucleating agents, and the effect of the interaction force between organic nucleating agents and PLA molecular chains on the crystallization behavior of PLA is analyzed. The effects of the crystallization behavior of PLA on its mechanical properties and heat resistance are discussed. It will provide a theoretical reference for the development and application of high-efficiency nucleating agents.
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