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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

240
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
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Psychosurgery01:30

Psychosurgery

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Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
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Electroconvulsive Therapy01:30

Electroconvulsive Therapy

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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

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Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
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Related Experiment Video

Updated: Aug 10, 2025

Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
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Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

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Recent advances in epilepsy surgery.

Mauricio Medina-Pizarro1, Dennis D Spencer, Eyiyemisi C Damisah

  • 1Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.

Current Opinion in Neurology
|February 10, 2023
PubMed
Summary

Technological advancements are improving epilepsy surgery with better imaging, AI-driven predictions, and minimally invasive techniques. Early surgical evaluation is crucial for patients with ongoing seizures to optimize treatment outcomes.

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Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
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Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
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Area of Science:

  • Neurology
  • Neurosurgery
  • Medical Technology

Background:

  • Epilepsy surgery has seen significant technological advancements in the last decade.
  • Comprehensive epilepsy centers are integrating new diagnostic tools and surgical techniques.

Approach:

  • Review of recent innovations in preoperative evaluation, surgical techniques, and outcome prediction.
  • Emphasis on high-resolution imaging, machine learning for data analysis, and robotic-assisted electrode placement.

Key Points:

  • Advanced imaging detects subtle abnormalities, while machine learning enhances prediction models for personalized treatment.
  • Robotic-assisted depth electrode placement improves safety and understanding of seizure networks in drug-resistant epilepsy.
  • Minimally invasive techniques offer alternatives for ablating or disrupting epileptogenic regions, with ongoing research into long-term efficacy.

Conclusions:

  • Epilepsy surgery remains underutilized globally; patients with refractory seizures should be considered for surgical candidacy.
  • Collaboration among epilepsy centers is vital for advancing research on network dynamics and surgical outcomes.