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[Expert recommendations on the use of teduglutide in pediatric patients with short bowel syndrome]
María Inés Martínez1, Martín Balacco2, Verónica Busoni3
1Hospital Universitario Fundación Favaloro, Buenos Aires, Argentina.
Insights
Short bowel syndrome in children is rare but serious. Expert-led intestinal rehabilitation and teduglutide (a GLP-2 analog) can improve outcomes for these pediatric patients.
Area of Science:
- Pediatric Gastroenterology
- Endocrinology
- Drug Development
Abstract:
Short bowel syndrome is a low-incidence disorder among pediatric patients, but it is associated with high morbidity and mortality rates. Management of these patients by an interdisciplinary team of experts focused on intestinal rehabilitation improves short- and long-term outcomes. Available resources for treatment include teduglutide, a glucagon-like peptide type 2 (GLP-2) analog made by recombinant techniques. Considering the available evidence and the authors' experience, Delphi-based recommendations for the use of teduglutide are suggested for healthcare professionals who treat pediatric patients with short bowel syndrome, as well as for health authorities.
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