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Post-Covid Orofacial Mucormycosis: A Clinico-Radiological Classification System and Management Protocol
Kapil Tomar1, I D Roy1, Mohan Rangan1
1Dept of Dental Surgery & Oral Health Sciences, Division of Oral and Maxillofacial Surgery, Armed Forces Medical College, Solapur Road, Pune, Maharashtra 411040 India.
Journal of Maxillofacial and Oral Surgery
|February 13, 2023
Summary
Post-COVID orofacial mucormycosis, a serious fungal infection, is linked to SARS-COV2 and corticosteroid use. This study introduces a clinico-radiological staging system and management protocol for affected patients.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Otolaryngology
Background:
- COVID-19 pandemic led to increased cases of orofacial mucormycosis.
- SARS-COV2 infection causes immunocompromise, creating a risk for opportunistic mucormycosis.
- Corticosteroid use and COVID-induced hyperglycemia exacerbate mucormycosis progression.
Purpose of the Study:
- Develop a clinico-radiological staging system for post-COVID mid-face mucormycosis.
- Establish a comprehensive management protocol for maxillofacial mucormycosis patients.
Main Methods:
- Retrospective study of 31 post-COVID mucormycosis patients.
- Combined clinical and radiological features to create a staging system.
- Developed a management protocol including cultures, surgery, and chemotherapy.
Main Results:
- A clinico-radiological staging system was formulated.
- Patient distribution across stages: Stage 0 (2), Stage 1-A (12), Stage 1-B (8), Stage 3 (6).
- A detailed management protocol was established.
Conclusions:
- A need for a comprehensive staging and management system for maxillofacial mucormycosis was identified.
- The proposed clinico-radiological system and management protocol address this need.
- This study provides a framework for managing post-COVID mucormycosis.
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