Lentigo maligna presenting as an eczematous lesion

Area of Science:

• Dermatology
• Oncology
• Pathology

Background:

• Lentigo maligna is an early form of melanoma in situ.
• It typically presents as a slowly growing, pigmented macule or patch.
• Atypical presentations can pose diagnostic challenges.

Observation:

• A case of lentigo maligna mimicking an eczematous lesion is described.
• This presentation differs from previously documented dermatitic manifestations of lentigo maligna.
• The lesion exhibited features suggestive of eczema clinically.

Findings:

• Microscopic examination of the excised specimen revealed significant hyperpigmentation.
• This histological finding of hyperpigmentation was notable in the context of an eczematous-appearing lesion.
• The case underscores the variability in lentigo maligna morphology.

Implications:

• Clinicians should consider lentigo maligna in the differential diagnosis of eczematous skin lesions, especially when atypical features are present.
• Histopathological examination is crucial for accurate diagnosis, particularly when clinical presentation is unusual.
• Increased awareness of diverse lentigo maligna presentations can improve early detection and patient outcomes.