Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

1.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.1K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

2.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.6K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

628
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
628
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

2.8K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.8K
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

309
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
309
Teratogenicity01:07

Teratogenicity

2.6K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nausea and Vomiting During Pregnancy.

American family physician·2026
Same author

Pharmacologic Management of Insomnia in Adults.

Primary care·2026
Same author

Beyond the Stethoscope: Point-of-Care Ultrasound (POCUS) as the New Norm in Family Medicine.

Journal of the American Board of Family Medicine : JABFM·2026
Same author

Factors Influencing Changing Scopes of Practice Among Contemporary Graduates of the Nation's Largest Family Medicine Residency.

Journal of the American Board of Family Medicine : JABFM·2025
Same author

Management of Chronic Heart Failure with Reduced Ejection Fraction.

Journal of the American Board of Family Medicine : JABFM·2024
Same author

How best to diagnose and manage abdominal aortic aneurysms.

The Journal of family practice·2023

Related Experiment Video

Updated: Aug 10, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

11.9K

Common Issues in Prenatal Care: Gestational Diabetes.

Allison Kolker1, Nicholas LeFevre2, R Levi Sundermeyer3

  • 1Texas A&M University School of Medicine Family Medicine Residency, 2900 East 29th Street Suite 100, Bryan, TX 77802.

FP Essentials
|February 13, 2023
PubMed
Summary
This summary is machine-generated.

Screening for gestational diabetes uses 1-step or 2-step methods. Management involves lifestyle changes, with medication and specific delivery timing if needed, plus postpartum screening for type 2 diabetes risk.

More Related Videos

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
06:11

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Published on: May 17, 2024

727
Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy
05:17

Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy

Published on: April 5, 2024

869

Related Experiment Videos

Last Updated: Aug 10, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

11.9K
Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
06:11

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Published on: May 17, 2024

727
Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy
05:17

Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy

Published on: April 5, 2024

869

Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Public Health

Background:

  • Gestational diabetes (GDM) affects pregnant individuals, necessitating effective screening and management strategies.
  • Two primary screening methods, the 1-step and 2-step approaches, are utilized for GDM detection.
  • Early detection and management are crucial for maternal and fetal well-being.

Purpose of the Study:

  • To outline current screening protocols for gestational diabetes.
  • To detail management strategies, including lifestyle modifications and pharmacotherapy.
  • To provide guidance on delivery timing and postpartum follow-up for GDM patients.

Main Methods:

  • Screening via 1-step (75-g, 2-hr OGTT) or 2-step (50-g, 1-hr glucose challenge test followed by OGTT if positive) oral glucose tolerance tests (OGTT).
  • Management focused on lifestyle modifications, with pharmacologic intervention (insulin, metformin, glyburide) for persistent hyperglycemia.
  • Antenatal fetal surveillance and specific delivery timing recommendations based on GDM control.

Main Results:

  • Screening is recommended between 24-28 weeks gestation for all pregnant individuals without pre-existing diabetes.
  • Lifestyle changes effectively manage GDM in most cases; medication is reserved for persistent hyperglycemia.
  • Delivery timing varies based on GDM control: 39 0/7–40 6/7 weeks for diet-controlled, and 39 0/7–39 6/7 weeks for drug-controlled GDM.

Conclusions:

  • Gestational diabetes requires timely screening and tailored management, including lifestyle adjustments and potential medication.
  • Patients with GDM face an elevated risk of developing type 2 diabetes postpartum, necessitating ongoing monitoring.
  • Postpartum screening with OGTT is recommended 4-12 weeks after delivery and periodically thereafter.