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Updated: Aug 10, 2025
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Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
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Prior Spontaneous or Induced Abortion Is a Risk Factor for Cervical Dysfunction in Pregnant Women: a Systematic
Julia J Brittain1, Stacey E Wahl2, Jerome F Strauss3,4
1Healthcare Studies, University of Richmond, Richmond, VA, USA.
Reproductive Sciences (Thousand Oaks, Calif.)
|February 13, 2023
Summary
A history of abortion increases the risk of cervical dysfunction in future pregnancies. This risk is higher with induced abortions, particularly surgical procedures, and increases with the number of prior abortions.
Area of Science:
- Obstetrics and Gynecology
- Reproductive Health Research
- Clinical Epidemiology
Background:
- A history of abortion is linked to cervical dysfunction in subsequent pregnancies.
- Uncertainty exists regarding risk stratification based on abortion type, procedure, or prior history.
- This study aimed to clarify the relationship between prior termination history and cervical dysfunction.
Approach:
- A comprehensive meta-analysis was conducted, searching Embase and Medline databases from 1960 to 2022.
- Six studies, totaling 2,513,044 pregnancies, met inclusion criteria and were analyzed.
- Cervical dysfunction was defined as cervical insufficiency/incompetence or short cervix.
Key Points:
- A history of induced or spontaneous abortion was associated with a 2.71-fold increased odds of cervical dysfunction.
- Induced abortions (surgical/medical) showed a 2.54-fold increased odds.
- Surgical abortions specifically demonstrated a 4.08-fold increased odds of cervical dysfunction.
Conclusions:
- Prior abortion history, especially induced abortions, is significantly associated with cervical dysfunction.
- The risk of cervical dysfunction is dependent on the type and number of previous abortions.
- Findings highlight the importance of considering abortion history in managing pregnancy risks.
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