Related Experiment Video
Updated: Aug 28, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
[Desmoplastic trichoepithelioma. Clinical aspects, histology and differential diagnosis]
1Institut für Pathologie, Universität Oulu.
Abstract:
Twelve desmoplastic trichoepitheliomas (DT) including one recurrent tumor from 9 patients are described by their clinical and histopathological features with special reference to the differential diagnostic aspects. DT typically appear as dimple lesions with raised edges in the faces of young females and histologically is composed of epithelial sheets and keratinized or calcified cysts in a desmoplastic stroma. A case showing cellular pleomorphism and followed by a relapse may represent an aggressive variant of DT. DT must be distinguished from syringoma, trichoepithelioma and especially basal cell carcinoma (BCC).
Related Concept Videos
Clinical Applications of Epidermal Stem Cells
Cells of the Epidermis
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Reticular Dermis
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

