Sugar Molecules Detection via C₂N Transistor-Based Sensor: First Principles Modeling

Real-time detection of sugar molecules is critical for preventing and monitoring diabetes and for food quality evaluation. In this article, a field effect transistor (FET) based on two-dimensional nitrogenated holey graphene (C₂N) was designed, developed, and tested to identify the sugar molecules including xylose, fructose, and glucose. Both density functional theory and non-equilibrium Green's function (DFT + NEGF) were used to study the designed device. Several electronic characteristics were studied, including work function, density of states, electrical current, and transmission spectrum. The proposed sensor is made of a pair of gold electrodes joint through a channel of C₂N and a gate was placed underneath the channel. The C₂N monolayer distinctive characteristics are promising for glucose sensors to detect blood sugar and for sugar molecules sensors to evaluate food quality. The electronic transport characteristics of the sensor resulted in a unique signature for each of the sugar molecules. This proposed work suggests that the developed C₂N transistor-based sensor could detect sugar molecules with high accuracy.