Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Stress and Mental Health

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...

Psychological Responses to Stress

Psychological Responses to Stress

Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...

Introduction to Stress and Lifestyle

Introduction to Stress and Lifestyle

Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...

Types of Stressors

Types of Stressors

A stressor is any event, condition, or stimulus that triggers stress and causes a physical or psychological response in the body. Stressors can be categorized into three main types: catastrophes; significant life changes; and daily hassles, including social stress. Each can be detrimental to physical and mental well-being.
Catastrophes
Catastrophes refer to large-scale, unpredictable events that create overwhelming stress and a sense of threat. Examples include natural disasters like...

Anxiety: Overview

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[The potential of a selective anxiolytic afobazole in clinical practice].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

Same author

[Transitional cognitive syndrome: Reconsidered classification of cognitive disorders].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

Same author

[Rapidly progressive cognitive impairment as a single clinical manifestation of anti-NMDA receptor encephalitis].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

Same author

[New Opportunities in the Treatment of Moderate Cognitive Impairment: Results of the Millennium Study in Real Clinical Practice].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

Same author

[Clinical and kinematic analysis of swimming disorders in Parkinson's disease].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

Same author

[The patient pathway in the diagnosis and treatment of mild cognitive impairment and new therapeutic opportunities. Resolution of the Expert Council (Moscow, April 21, 2025)].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2025

Search research articles

Related Experiment Video

Updated: Aug 8, 2025

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm

Published on: May 4, 2020

Stress, Asthenia, and Cognitive Disorders.

E E Vasenina¹, O A Gankina¹, O S Levin¹

¹Russian Medical Academy of Continuous Professional Education, Russian Ministry of Health, Moscow, Russia.

Neuroscience and Behavioral Physiology

|February 27, 2023

Summary

Asthenia, a symptom of energy depletion, can become a disabling condition like chronic fatigue syndrome. This syndrome often involves cognitive and affective disorders, complicating diagnosis.

Keywords:

affective disorders asthenia chronic fatigue syndrome cognitive impairment treatment

More Related Videos

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents

Published on: July 10, 2017

Related Experiment Videos

Last Updated: Aug 8, 2025

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm

Published on: May 4, 2020

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents

Published on: July 10, 2017

Area of Science:

Neurology
Immunology
Psychiatry

Background:

Asthenia is a common clinical syndrome observed across various diseases, including somatic, infectious, and neurological conditions.
Initially a protective response to energy depletion, asthenia can evolve into a severe, pathological state.
Asthenia can progress to chronic fatigue syndrome, an immune-mediated disease, and is frequently associated with cognitive and affective disturbances.

Purpose of the Study:

To explore the intricate relationship between asthenia, chronic fatigue syndrome, and associated cognitive and affective disorders.
To elucidate the diagnostic challenges posed by the co-occurrence of these conditions.

Main Methods:

Literature review
Clinical case analysis
Syndromic pattern recognition

Main Results:

Asthenia's progression from a protective mechanism to a pathological entity is detailed.
The link between asthenia, chronic fatigue syndrome, and the manifestation of cognitive and affective disorders is established.
Diagnostic complexities arising from the overlap of these conditions are highlighted.

Conclusions:

Asthenia, chronic fatigue syndrome, and cognitive/affective disorders represent a complex interplay of physiological and psychological factors.
Understanding these interconnections is crucial for accurate diagnosis and effective management of patients presenting with asthenia.