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Updated: Aug 5, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
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Sleep Disorders in Post-COVID Syndrome: A Psychiatric or Neurological Problem?

O V Kotova1,2, V E Medvedev1, M G Poluektov3

  • 1Peoples' Friendship University of Russia, Moscow, Russia.

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|March 27, 2023
PubMed
Summary
This summary is machine-generated.

Post-COVID syndrome (PCS) can cause long-term health issues, including anxiety, depression, and sleep disorders like coronasomnia. Anti-anxiety medications Noofen and Adaptol show promise in managing these persistent symptoms.

Keywords:
COVID-19COVIDsomniaantianxiety therapyanxietycoronavirusdepressionmental healthpost-COVID syndromesleep disorders

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Area of Science:

  • Neurology
  • Psychiatry
  • Infectious Diseases

Background:

  • COVID-19 causes prolonged health issues beyond the acute phase, affecting a significant percentage of survivors.
  • Post-COVID syndrome (PCS) includes mental health impacts like anxiety and depression (affecting ~30%) and sleep disorders (coronasomnia, affecting ~33%).
  • The bidirectional relationship between mental health and sleep disturbances complicates PCS management.

Purpose of the Study:

  • To investigate the efficacy of anti-anxiety medications in managing persistent symptoms of post-COVID syndrome.
  • To explore the potential of Noofen and Adaptol in correcting sleep disorders associated with PCS.
  • To address the challenges in managing PCS due to the interplay of mental health and sleep disturbances.

Main Methods:

  • Review of clinical data on patients experiencing post-COVID syndrome.
  • Analysis of the impact of anti-anxiety medications (Noofen, Adaptol) on PCS symptoms.
  • Examination of the correlation between mental health status and sleep quality in COVID-19 survivors.

Main Results:

  • Approximately 10-20% of COVID-19 patients experience prolonged recovery beyond three weeks.
  • At least 30% of recovered patients develop anxiety and/or depression.
  • A 42% increase in sleep disorders, termed coronasomnia, is reported among COVID-19 survivors.
  • Noofen and Adaptol are presented as potential therapeutic agents for PCS-related sleep and anxiety issues.

Conclusions:

  • Post-COVID syndrome presents complex long-term health challenges, including significant mental health and sleep disturbances.
  • Effective management of PCS requires addressing the intertwined nature of anxiety, depression, and sleep disorders.
  • Anti-anxiety drugs Noofen and Adaptol offer a potential therapeutic avenue for mitigating PCS manifestations, particularly coronasomnia.