Related Experiment Video
Updated: Aug 8, 2025

10:14
Double-stranded RNA Oral Delivery Methods to Induce RNA Interference in Phloem and Plant-sap-feeding Hemipteran Insects
Published on: May 4, 2018
13.9K
[Strategies for exogenous RNA delivery in RNAi-mediated pest management]
Liu'e Gong1,2, Shumin Ying2,3, Yafen Zhang1
1College of Life Science, China Jiliang University, Hangzhou 310018, Zhejiang, China.
Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|February 27, 2023
Summary
RNA interference (RNAi) offers a novel biotechnology for pest control, overcoming limitations of traditional methods. Nanoparticle delivery systems show promise for effective RNAi-based crop protection against diseases and pests.
Area of Science:
- Agricultural Science
- Biotechnology
- Molecular Biology
Background:
- Traditional pest management faces challenges like environmental pollution and resistance.
- RNA interference (RNAi) is a gene regulation process with potential for pest control.
- Effective delivery of interference RNA is crucial for RNAi-based pest management.
Approach:
- Reviewing advances in RNAi mechanisms and delivery systems.
- Summarizing strategies for exogenous RNA delivery in pest control.
- Highlighting nanoparticle complexes for efficient dsRNA delivery.
Key Points:
- RNAi technology provides a sustainable alternative to conventional pesticides.
- Overcoming delivery challenges is key to successful RNAi applications in agriculture.
- Nanoparticle-based delivery enhances the efficacy of RNAi for crop protection.
Conclusions:
- RNAi-based strategies represent a significant advancement in pest control.
- Nanoparticle complexes offer a promising solution for dsRNA delivery challenges.
- Further research into RNA delivery systems will enhance agricultural sustainability.
Related Concept Videos
Experimental RNAi
6.2K
RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing its transcription or activating the RNA degradation process. The mechanism was discovered by Andrew Fire and Craig Mello in 1998 in plants. Today, it is observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals. This precise cellular mechanism of gene silencing has been developed into a technique that provides an efficient way to identify and determine the...
6.2K
RNA Interference
26.2K
RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...
26.2K
siRNA - Small Interfering RNAs
16.9K
Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the...
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the...
16.9K

