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Updated: Aug 8, 2025

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
Integrating a fluorinated photoactive chromophore into metal-organic frameworks for selective trifluoroethylation of
Leixin Hou1, Xu Jing1, Huilin Huang1
1State Key Laboratory of Fine Chemicals, Zhang Dayu College of Chemistry, Dalian University of Technology, 116024, P. R. China. xjing@dlut.edu.cn.
Abstract:
In this study, we report on a fluorinated photoactive metal-organic framework (MOF), Zn-TFBD, capable of excellent light harvesting ability and higher water-assisted proton conductivity. Upon visible-light irradiation, selective 2,2,2-trifluoroethylation of 4-methoxystyrene was achieved on the heterogeneous photocatalyst, Zn-TFBD. This work has enriched the applications of fluorinated MOFs in the field of water-mediated organic transformations.

