Related Experiment Video
Updated: Aug 8, 2025
Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
Published on: February 16, 2018
Electropolymerized molecularly imprinted polypyrrole film for dimethoate sensing: investigation on template removal
Marlene Valentino1, Anna Imbriano2, Angelo Tricase1,2
1Department of Chemistry, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy. paolo.bollella@uniba.it.
Abstract:
The development of ultrasensitive analytical detection methods for organophosphorus pesticides such as dimethoate (DMT) plays a key role in healthy food production. DMT is an inhibitor of acetylcholinesterase (AChE), which can lead to the accumulation of acetylcholine and result in symptoms related to the autonomous and central nervous systems. Herein, we report the first spectroscopic and electrochemical study on template removal after an imprinting process from a polypyrrole-based molecularly imprinted polymer (PPy-MIP) film for the detection of DMT. Several template removal procedures were tested and evaluated using X-ray photoelectron spectroscopy. The most effective procedure was achieved in 100 mM NaOH. The proposed DMT PPy-MIP sensor exhibits a limit of detection of (8 ± 2) × 10-12 M.
