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Adult-onset Still's disease after SARS-Cov-2 infection
Tayssir Ben Achour1, Wiem Ben Elhaj1, Maysam Jridi1
1Rabta University Hospital Center Tunis Tunisia.
Clinical Case Reports
|March 6, 2023
Summary
Adult-onset Still's disease (AOSD) is a rare inflammatory condition. This case study highlights how SARS-CoV-2 infection can trigger AOSD, presenting with fever and joint pain post-COVID-19.
Area of Science:
- Rheumatology
- Infectious Diseases
- Immunology
Background:
- Adult-onset Still's disease (AOSD) is a rare systemic autoinflammatory disorder.
- SARS-CoV-2 infection is known to trigger various inflammatory and autoimmune conditions.
- Shared clinical and laboratory features exist between AOSD and SARS-CoV-2 infection, notably systemic inflammation.
Observation:
- A 19-year-old female presented with prolonged fever (3 weeks), arthralgia, and laboratory evidence of systemic inflammation.
- The patient's symptoms emerged following a SARS-CoV-2 infection.
Findings:
- A diagnosis of post-COVID-19 Adult-onset Still's disease was established.
- This case suggests a potential causal link between SARS-CoV-2 infection and the development of AOSD.
Implications:
- SARS-CoV-2 infection may act as an environmental trigger for AOSD in susceptible individuals.
- Understanding this association is crucial for diagnosing and managing inflammatory conditions post-COVID-19.
- Further research is warranted to elucidate the mechanisms underlying SARS-CoV-2-induced AOSD.
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