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Updated: Aug 7, 2025

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model
Published on: January 13, 2023
Soft and Hard Tissue Changes Subsequent to Spontaneous Healing of the Extraction Sockets Using Cone-Beam Computed
Yaser Safi1, Behnoosh Behnam2, Reza Amid3
1Oral and Maxillofacial Radiology Department, Dental School, Shahid Beheshti University of Medical Sciences, Evin, Tehran, Iran.
Objective:
This study sought to compare the thickness of hard and soft tissues between edentulous and contralateral tooth sites.
Materials And Methods:
This split-mouth study evaluated 153 partially edentulous patients. The measurements were made on cone-beam computed tomography (CBCT) scans. The soft tissue thickness was measured at the cementoenamel junctional (CEJ) level, and at 2, 4, and 6 mm apical to the CEJ in the facial and palatal aspects. The bone thickness of the opposite quadrant was also recorded at 2, 4, and 6 mm apical to the CEJ. The Mann-Whitney U test and the Spearman's rank correlation coefficient were applied for further statistical analyses.
Results:
At the edentulous sites, significant soft tissue loss was noted at the CEJ level (p < 0.0001) and a considerable gain was noted at 2, 4, and 6 mm apical to the CEJ (p = 0.004, p < 0.0001, p ≤ 0.0001, respectively). A significant hard tissue loss was noted at 2 mm apical to the CEJ but a significant hard tissue gain was observed at the edentulous sites (p < 0.0001). The soft tissue gain at 6 mm apical to the CEJ was significantly associated with an increase in buccolingual diameter (p = 0.004) while the hard tissue loss at 2 mm apical to the CEJ was significantly correlated with a reduction in buccolingual diameter (p = 0.020).
Conclusion:
Different amounts of tissue thickness alterations occurred in different levels of socket.

