New Staging System and Prognostic Model for Malignant Phyllodes Tumor Patients without Distant Metastasis: A
Zhaohui Ruan1,2, Qi Quan1, Qianyu Wang1
1Department of VIP Section, Sun Yat-sen University Cancer Center, State Key Laboratory Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, China.
Journal of Clinical Medicine
|March 11, 2023
Summary
This study developed a new staging system and prognostic models for male breast cancer (MPTB) patients. These tools aid in predicting outcomes and understanding prognostic factors for MPTB.
Area of Science:
- Oncology
- Clinical Research
Background:
- Male breast cancer (MPTB) is a rare disease.
- Existing staging and prognostic systems may not fully capture MPTB's unique characteristics.
Purpose of the Study:
- To develop a novel staging system for MPTB.
- To create new prognostic models specifically for MPTB patients.
Main Methods:
- Comprehensive data analysis using the SEER database.
- Comparison of 1085 MPTB cases with 382,718 invasive ductal carcinoma cases.
Main Results:
- Established a new stage- and age-stratification system for MPTB.
- Developed and validated two prognostic models for MPTB patients using multifaceted and multidata verification.
Conclusions:
- The new staging system and prognostic models enhance understanding of MPTB.
- These tools assist in predicting patient outcomes and identifying key prognostic factors for MPTB.
