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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

511
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
511
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Glaucoma: Overview01:25

Glaucoma: Overview

665
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
665

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Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
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Update on Retinal Vein Occlusion.

Francesco Romano1, Francesca Lamanna1, Pierre Henry Gabrielle2

  • 1Eye Clinic, Department of Biomedical and Clinical Science, Luigi Sacco Hospital, University of Milan, Milan, Italy.

Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
|March 13, 2023
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This summary is machine-generated.

Retinal vein occlusion, a leading vascular disorder, requires cardiovascular risk assessment. Advances in imaging and treatments like anti-VEGF injections improve outcomes, though new therapies are emerging.

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Area of Science:

  • Ophthalmology
  • Vascular Medicine
  • Medical Imaging

Background:

  • Retinal vein occlusion (RVO) is the second leading cause of retinal vascular disorders globally.
  • Consistent sex distribution worldwide necessitates comprehensive cardiovascular risk factor evaluation.
  • RVO diagnosis and management have evolved significantly over 30 years.

Conclusions:

  • Long-term outcomes for RVO have improved, with novel treatments like gene therapy under development.
  • Multimodal imaging and diverse treatment strategies are key to managing RVO.
  • Despite progress, some cases present sight-threatening complications requiring aggressive management.