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The Murine Choline-Deficient, Ethionine-Supplemented CDE Diet Model of Chronic Liver Injury
Published on: October 21, 2017
Plants-based medicine implication in the evolution of chronic liver diseases
Monica Foghis1, Simona Gabriela Bungau2, Alexa Florina Bungau1
1Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, Oradea 410073, Romania.
This review explores medicinal plants for liver disease, highlighting their potential for new drugs. More research is needed to assess safety, effectiveness, and patient quality of life for these herbal treatments.
Area of Science:
- Pharmacology
- Hepatology
- Ethnobotany
Background:
- Hepatic disorders pose significant global health challenges.
- Many patients with chronic liver disease use herbal medicines alongside conventional treatments.
- Existing research often lacks comprehensive data on patient quality of life and disease progression with herbal therapies.
Purpose of the Study:
- To review medicinal plants, their bioactive compounds, and effects on chronic liver disease.
- To identify gaps in current research regarding patient outcomes and quality of life.
- To explore the potential of phytocomponents in developing novel therapeutic strategies for liver ailments.
Main Methods:
- Comprehensive literature review of studies on medicinal plants for liver disorders.
- Analysis of bioactive compounds and their reported activities.
- Evaluation of evidence on the impact of herbal medicines on disease progression and patient well-being.
Main Results:
- Identified key medicinal plant species and their bioactive constituents used in liver disease management.
- Highlighted the frequent lack of comprehensive data on patient quality of life and long-term outcomes.
- Confirmed the potential of bioactive phytocomponents as a source for new drug development.
Conclusions:
- Medicinal plants show promise for treating liver disorders, with potential for novel drug discovery.
- There is a critical need for high-quality preclinical studies to evaluate safety, efficacy, and standardization.
- Future research must incorporate patient-reported outcomes and quality of life measures for a holistic assessment of herbal treatments.
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