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Updated: Aug 6, 2025
Neural Tube Closure in Mouse Whole Embryo Culture
Published on: October 21, 2011
Neural Tube Defects from Antenatal Diagnosis to Discharge - a Tertiary Academic Centre Experience
Heidi Al-Wassia1, Hanan Bamanie2, Haneen Rahbini2
1Department of Pediatrics, Division of Neonatology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Background:
Bleeding Worldwide, approximately 300,000 infants are born annually with neural tube defects (NTDs), which carry a high risk of morbidity and mortality.
Objective:
The aim of the study was to describe the experience with NTD patients born at a tertiary academic center.
Methods:
A retrospective record review of all neonates with NTD admitted to the neonatal intensive care unit over six years.
Results:
Out of the 39 patients identified, 32 (82.1%) were diagnosed antenatally. Most NTD cases were of the myelomeningocele 26 (66.7%) type. The most common site of the myelomeningocele was lumbar, and the thoracolumbar site had the worst prognosis.
Conclusion:
Early detection of the disease allows better planning of delivery and treatment decisions. Nevertheless, understanding the magnitude of the problem necessitates adopting public health prevention strategies for better outcomes.
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